Go











3505 E. Frontage Rd.
Suite 315
Tampa, FL 33607
800-749-2257 phone
813-636-8122 fax
info@aakp.org

  
Gene Variations Associated with Kidney Disease Among African-Americans

Research conducted by the National Institutes of Health (NIH) found several types of a single gene are strongly associated with kidney disease, especially among African-Americans. The gene MYH9 and its many variations greatly contribute to the increased risk of kidney disease in African-Americans.
 
MYH9 variants are associated with focal segmental glomerulosclerosis (FSGS), HIV-associated FSGS and all non-diabetic kidney failure. These variants were much more frequent among people of African ancestry than among whites. The increased risk among African-Americans with these variants is more than 300 percent for FSGS, more than 500 percent for HIV-associated FSGS, and more than 100 percent for all non-diabetic kidney failure. Sixty percent of African-Americans carry the risk variants in contrast to 4 percent of whites.
 
AAKP recently teamed up with Baxter Healthcare to promote the Take 2 Tell 5 program. This campaign targets African Americans with kidney disease and those at risk of developing kidney failure, to take two minutes to get tested for the disease and tell five friends and loved ones to also get tested.

This article originally appeared in the October 2008 issue of Kidney Beginnings: The Electronic Newsletter.

 


Back
 
© 1999-2012 American Association of Kidney Patients, Inc. All rights reserved. Unauthorized use prohibited. The information contained in the American Association of Kidney Patients (AAKP) Web site is not a substitute for medical advice or treatment, and the AAKP recommends consultation with your doctor or healthcare professional. To view Terms of Usage for the AAKP Web site, please click here. Website design by Gecko Media.